Genome-scale metabolic models

panGEMs Browser

Interactive explorer for 4,659 strain-specific genome-scale metabolic models (GEMs) — 2,313 Escherichia coli (EcopanGEM) and 2,346 Lactobacillaceae across 26 species (LactoPanGEM)

Open Flux Studio Analytics and comparison compare models, contrast cohorts, build clustermaps, explore the species tree
Simulate any of these models in Flux Studio Thirteen analyses — flux balance, knockouts, gene essentiality, flux sampling, strain design — on 12,340 curated growth media. Nothing installs and nothing uploads: the solver runs in your own browser tab.
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Live usage since launch · updated hourly
The collection at a glance
4,659 genome-scale models across two pangenomes — model size, taxonomic breadth, and where the strains were isolated.
Model size distribution
Two distinct size regimes: compact Lactobacillaceae models vs larger E. coli models.
Lactobacillaceae genomes per species
26 species · the E. coli collection adds 2,313 models as a single species.
Isolation geography
Strains with a recorded isolation country (98% mapped), shaded by number of models. Hover for details · click a country to filter the table below.
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How to use: Filter by Dataset (EcopanGEM / LactoPanGEM) or Organism, or search the table. Click a GEM File to inspect its reactions, metabolites and genes in the browser. Select rows and use Download Selected GEMs to fetch just those models (packaged client-side, no server), or Download All GEMs for the full archives. Every model is a COBRApy-compatible JSON.