Genome-scale metabolic models

LactoPanGEM Browser

Interactive explorer for 2,346 strain-specific genome-scale metabolic models (GEMs) spanning the Lactobacillaceae family — 28 species across 12 genera, each model browsable, filterable and downloadable in your browser

Open Flux Studio Analytics and comparison compare models, contrast cohorts, build clustermaps, explore the species tree
Simulate any of these models in Flux Studio Thirteen analyses — flux balance, knockouts, gene essentiality, flux sampling, strain design — on 12,340 curated growth media. Nothing installs and nothing uploads: the solver runs in your own browser tab.
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GEMs Available
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GEM Downloads
Live usage since launch · updated hourly
The collection at a glance
2,346 genome-scale models across the Lactobacillaceae family — model size, taxonomic breadth, and where the strains were isolated.
Model size distribution
Lactobacillaceae GEMs are compact: most carry 1,100–1,500 reactions, reflecting the small, streamlined genomes of the family.
Genomes per species
28 species (GTDB) across 12 genera · Lactiplantibacillus plantarum is the deepest sampled.
Isolation geography
Strains with a recorded isolation country (98% mapped), shaded by number of models. Hover for details · click a country to filter the table below.
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How to use: Filter by Genus or Organism, or search the table. Click a GEM File to inspect its reactions, metabolites and genes in the browser. Select rows and use Download Selected GEMs to fetch just those models (packaged client-side, no server), or Download All GEMs for the full archives. Every model is a COBRApy-compatible JSON.